Gene set association test identifies sex-specific pathways associated with type 2 diabetes

Gene set association test identifies sex-specific pathways associated with type 2 diabetes

Single variant analysis in genome-wide association studies (GWAS) has been proven to be successful in identifying thousands of genetic variants associated with hundreds of complex diseases. However, these identified variants only explain a small fraction of inheritable variability in many diseases,...

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Bibliographic Details
Main Authors: Tao eHe, Ping-Shou eZhong, Yuehua eCui
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Genetics
Subjects:
correlated p-values
gene-based analysis
pathway-based analysis
p-value combination
sex-specific analysis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00395/full

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