Metformin Attenuates Monosodium-Iodoacetate-Induced Osteoarthritis via Regulation of Pain Mediators and the Autophagy–Lysosomal Pathway

Metformin Attenuates Monosodium-Iodoacetate-Induced Osteoarthritis via Regulation of Pain Mediators and the Autophagy–Lysosomal Pathway

Osteoarthritis (OA) is the most common degenerative arthritis associated with pain and cartilage destruction in the elderly; it is known to be involved in inflammation as well. A drug called celecoxib is commonly used in patients with osteoarthritis to control pain. Metformin is used to treat type 2...

Full description

Bibliographic Details
Main Authors: Hyun Sik Na, Ji Ye Kwon, Seon-Yeong Lee, Seung Hoon Lee, A Ram Lee, Jin Seok Woo, KyungAh Jung, Keun-Hyung Cho, Jeong-Won Choi, Dong Hwan Lee, Hong-Ki Min, Sung-Hwan Park, Seok Jung Kim, Mi-La Cho
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
osteoarthritis
metformin
pain
cartilage
autophagy
combination therapy
Online Access:https://www.mdpi.com/2073-4409/10/3/681

Internet

https://www.mdpi.com/2073-4409/10/3/681

Similar Items