Prophylactic prednisolone for the prevention of early and intermediate adverse effects of radioactive iodine therapy in patients with thyroid cancer: study protocol for a single-centre, phase II/III, randomized, double-blinded, placebo-controlled clinical trial

Abstract Background Radioactive iodine (RAI) therapy is the standard adjuvant treatment for differentiated thyroid cancer (i.e. papillary and follicular). RAI is associated with troublesome early, intermediate and late adverse effects. Although glucocorticoids are used for the management of these ad...

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Bibliographic Details
Main Authors: Umesh Jayarajah, Mahilal Wijekoon, Sanjeewa A. Seneviratne
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Trials
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13063-020-04744-x