Comprehensive Pathogen Identification, Antibiotic Resistance, and Virulence Genes Prediction Directly From Simulated Blood Samples and Positive Blood Cultures by Nanopore Metagenomic Sequencing

Comprehensive Pathogen Identification, Antibiotic Resistance, and Virulence Genes Prediction Directly From Simulated Blood Samples and Positive Blood Cultures by Nanopore Metagenomic Sequencing

Bloodstream infection is a major cause of morbidity and mortality worldwide. We explored whether MinION nanopore sequencing could accelerate diagnosis, resistance, and virulence profiling prediction in simulated blood samples and blood cultures. One milliliter of healthy blood samples each from dire...

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Bibliographic Details
Main Authors: Menglan Zhou, Yarong Wu, Timothy Kudinha, Peiyao Jia, Lei Wang, Yingchun Xu, Qiwen Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
bloodstream infection
MinION nanopore sequencing
identification
resistance
virulence
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.620009/full

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