Technical challenges and limitations of current mouse models of ovarian cancer

Technical challenges and limitations of current mouse models of ovarian cancer

<p>Abstract</p> <p>The development of genetically engineered models (GEM) of epithelial ovarian cancer (EOC) has been very successful, with well validated models representing high grade and low grade serous adenocarcinomas and endometrioid carcinoma (EC). Most of these models were...

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Bibliographic Details
Main Authors: Garson Kenneth, Gamwell Lisa F, Pitre Elizabeth MG, Vanderhyden Barbara C
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Mouse models
Genetically engineered
Ovary
Oviduct
Ovarian surface epithelium
Online Access:http://www.ovarianresearch.com/content/5/1/39

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