Effects of Iron in Neonates and Young Infants: a Review
Iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. Iron is absorbed by the duodenum and requires an acidic environment for optimal absorption. Iron is found for 70% in erythrocytes, and 30% in storage, and a small amount in myoglobin and cytoch...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2016-07-01
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| Series: | International Journal of Pediatrics |
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| Online Access: | http://ijp.mums.ac.ir/article_6991_0334cb4ec696b917ae8e62b33105b936.pdf |
| Summary: | Iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. Iron is absorbed by the duodenum and requires an acidic environment for optimal absorption. Iron is found for 70% in erythrocytes, and 30% in storage, and a small amount in myoglobin and cytochromes. Iron supplementation reduces anemia in breastfed infants and increases in significant dose-dependent effects hemoglobin and ferritin levels, transferrin saturation, mean cell volume, and transferrin receptor levels. The prevalence of iron deficiency at 6 months of age is 36% in the placebo, 8.2% after 1 mg/kg per day, and 3.8% after 2 mg/kg per day iron (p |
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| ISSN: | 2345-5047 2345-5055 |