Pharmacological inhibition of STAT3 pathway ameliorates acute liver injury in vivo via inactivation of inflammatory macrophages and hepatic stellate cells

Abstract Liver diseases represent a major health problem worldwide, in particular, acute liver injury is associated with high mortality and morbidity. Inflammatory macrophages and hepatic stellate cells (HSCs) are known to be involved in the pathogenesis of acute liver injury. In this study, we have...

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Bibliographic Details
Main Authors: Büsra Öztürk Akcora, Alexandros Vassilios Gabriël, Ana Ortiz‐Perez, Ruchi Bansal
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2019-00070