Hybrid Modeling for Simultaneous Prediction of Flux, Rejection Factor and Concentration in Two-Component Crossflow Ultrafiltration
Ultrafiltration is a powerful method used in virtually every pharmaceutical bioprocess. Depending on the process stage, the product-to-impurity ratio differs. The impact of impurities on the process depends on various factors. Solely mechanistic models are currently not sufficient to entirely descri...
Main Authors: | Maximilian Krippl, Ignasi Bofarull-Manzano, Mark Duerkop, Astrid Dürauer |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Processes |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9717/8/12/1625 |
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