High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability.

The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose tissue, high fat diet (HFD)/obesity in mice does not...

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Bibliographic Details
Main Authors: Andrew M F Johnson, Anne Costanzo, Melanie G Gareau, Aaron M Armando, Oswald Quehenberger, Julie M Jameson, Jerrold M Olefsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4383570?pdf=render