Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature

Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature

The combination of central odontogenic fibroma and central giant cell granuloma is extremely rare and has been reported in only 46 cases worldwide in previous articles. The lesion is called a hybrid central odontogenic fibroma with central giant cell granuloma like lesion (HCOF-CGCG) due to a histop...

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Main Authors: Sakanus Vijintanawan, Kumar K C, Anchisa Aittiwarapoj, Natthamet Wongsirichat
Format: Article
Language:English
Published: Mahidol University 2019-09-01
Series:Siriraj Medical Journal
Subjects:
Central odontogenic fibroma; central giant cell granuloma; hybrid
Online Access:https://www.tci-thaijo.org/index.php/sirirajmedj/article/view/217292
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spelling doaj-e4d30d2a3c8244428898456672ddb5dc2020-11-25T02:13:27ZengMahidol UniversitySiriraj Medical Journal0125-152X2228-80822019-09-0171542643110.33192/Smj.2019.63217292Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the LiteratureSakanus Vijintanawan0Kumar K C1Anchisa Aittiwarapoj2Natthamet Wongsirichat3Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400Department of Oral Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok 10400, and Consultant of International College of Dentistry Committee, Walailuk University International College of Dentistry, Bangkok 10400The combination of central odontogenic fibroma and central giant cell granuloma is extremely rare and has been reported in only 46 cases worldwide in previous articles. The lesion is called a hybrid central odontogenic fibroma with central giant cell granuloma like lesion (HCOF-CGCG) due to a histopathological characteristics of multinucleated giant cell and odontogenic epithelium in fibro-cellular background. We report a case of HCOF-CGCG in a 27-year old Thai male patient who was identified as the first case in Thailand. Radiographic examination showed a well-defined radiolucency lesion at posterior mandibular area. Enucleation and curettage were done and microscopic study revealed a fibro-cellular proliferating tissue containing numerous strands, cord of odontogenic epithelium, and numerous multinucleated giant cells. This report also included a literature review of the previous 45 cases.https://www.tci-thaijo.org/index.php/sirirajmedj/article/view/217292Central odontogenic fibroma; central giant cell granuloma; hybrid
collection DOAJ
language English
format Article
sources DOAJ
author Sakanus Vijintanawan
Kumar K C
Anchisa Aittiwarapoj
Natthamet Wongsirichat
spellingShingle Sakanus Vijintanawan
Kumar K C
Anchisa Aittiwarapoj
Natthamet Wongsirichat
Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature
Siriraj Medical Journal
Central odontogenic fibroma; central giant cell granuloma; hybrid
author_facet Sakanus Vijintanawan
Kumar K C
Anchisa Aittiwarapoj
Natthamet Wongsirichat
author_sort Sakanus Vijintanawan
title Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature
title_short Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature
title_full Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature
title_fullStr Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature
title_full_unstemmed Hybrid Central Odontogenic Fibroma with Central Giant Cell Granuloma Like Lesion ; A Case Report and Review of the Literature
title_sort hybrid central odontogenic fibroma with central giant cell granuloma like lesion ; a case report and review of the literature
publisher Mahidol University
series Siriraj Medical Journal
issn 0125-152X
2228-8082
publishDate 2019-09-01
description The combination of central odontogenic fibroma and central giant cell granuloma is extremely rare and has been reported in only 46 cases worldwide in previous articles. The lesion is called a hybrid central odontogenic fibroma with central giant cell granuloma like lesion (HCOF-CGCG) due to a histopathological characteristics of multinucleated giant cell and odontogenic epithelium in fibro-cellular background. We report a case of HCOF-CGCG in a 27-year old Thai male patient who was identified as the first case in Thailand. Radiographic examination showed a well-defined radiolucency lesion at posterior mandibular area. Enucleation and curettage were done and microscopic study revealed a fibro-cellular proliferating tissue containing numerous strands, cord of odontogenic epithelium, and numerous multinucleated giant cells. This report also included a literature review of the previous 45 cases.
topic Central odontogenic fibroma; central giant cell granuloma; hybrid
url https://www.tci-thaijo.org/index.php/sirirajmedj/article/view/217292
work_keys_str_mv AT sakanusvijintanawan hybridcentralodontogenicfibromawithcentralgiantcellgranulomalikelesionacasereportandreviewoftheliterature
AT kumarkc hybridcentralodontogenicfibromawithcentralgiantcellgranulomalikelesionacasereportandreviewoftheliterature
AT anchisaaittiwarapoj hybridcentralodontogenicfibromawithcentralgiantcellgranulomalikelesionacasereportandreviewoftheliterature
AT natthametwongsirichat hybridcentralodontogenicfibromawithcentralgiantcellgranulomalikelesionacasereportandreviewoftheliterature
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