Molecular analysis of parturition via oxytocin receptor expression

Molecular analysis of parturition via oxytocin receptor expression

In daily obstetric practice, oxytocin is one of the most frequently used drugs to stimulate uterine contraction. However, uterine sensitivity to oxytocin is profoundly different among pregnant women, which may reflect oxytocin receptor (OTR) expression in the uterus. We review here the literature fo...

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Bibliographic Details
Main Authors: Tadashi Kimura, Kazuhide Ogita, Kei-ichi Kumasawa, Takuji Tomimatsu, Tateki Tsutsui
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
expression
oxytocin receptor
parturition
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455913000600
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spelling doaj-e4d048ce479f49b687bf1c936bbb36b52020-11-24T22:36:22ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592013-06-0152216517010.1016/j.tjog.2013.04.004Molecular analysis of parturition via oxytocin receptor expressionTadashi Kimura0Kazuhide Ogita1Kei-ichi Kumasawa2Takuji Tomimatsu3Tateki Tsutsui4Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, JapanDepartment of Obstetrics and Gynecology, Kawasaki Medical School, Kawasaki, JapanDepartment of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, JapanIn daily obstetric practice, oxytocin is one of the most frequently used drugs to stimulate uterine contraction. However, uterine sensitivity to oxytocin is profoundly different among pregnant women, which may reflect oxytocin receptor (OTR) expression in the uterus. We review here the literature focusing on OTR regulation in the human uterus. Recent progress in molecular biology has augmented our knowledge about OTR regulation in the uterus at the transcription level, although the totality of preparation for labor through OTR expression is still obscure.http://www.sciencedirect.com/science/article/pii/S1028455913000600expressionoxytocin receptorparturition
collection DOAJ
language English
format Article
sources DOAJ
author Tadashi Kimura
Kazuhide Ogita
Kei-ichi Kumasawa
Takuji Tomimatsu
Tateki Tsutsui
spellingShingle Tadashi Kimura
Kazuhide Ogita
Kei-ichi Kumasawa
Takuji Tomimatsu
Tateki Tsutsui
Molecular analysis of parturition via oxytocin receptor expression
Taiwanese Journal of Obstetrics & Gynecology
expression
oxytocin receptor
parturition
author_facet Tadashi Kimura
Kazuhide Ogita
Kei-ichi Kumasawa
Takuji Tomimatsu
Tateki Tsutsui
author_sort Tadashi Kimura
title Molecular analysis of parturition via oxytocin receptor expression
title_short Molecular analysis of parturition via oxytocin receptor expression
title_full Molecular analysis of parturition via oxytocin receptor expression
title_fullStr Molecular analysis of parturition via oxytocin receptor expression
title_full_unstemmed Molecular analysis of parturition via oxytocin receptor expression
title_sort molecular analysis of parturition via oxytocin receptor expression
publisher Elsevier
series Taiwanese Journal of Obstetrics & Gynecology
issn 1028-4559
publishDate 2013-06-01
description In daily obstetric practice, oxytocin is one of the most frequently used drugs to stimulate uterine contraction. However, uterine sensitivity to oxytocin is profoundly different among pregnant women, which may reflect oxytocin receptor (OTR) expression in the uterus. We review here the literature focusing on OTR regulation in the human uterus. Recent progress in molecular biology has augmented our knowledge about OTR regulation in the uterus at the transcription level, although the totality of preparation for labor through OTR expression is still obscure.
topic expression
oxytocin receptor
parturition
url http://www.sciencedirect.com/science/article/pii/S1028455913000600
work_keys_str_mv AT tadashikimura molecularanalysisofparturitionviaoxytocinreceptorexpression
AT kazuhideogita molecularanalysisofparturitionviaoxytocinreceptorexpression
AT keiichikumasawa molecularanalysisofparturitionviaoxytocinreceptorexpression
AT takujitomimatsu molecularanalysisofparturitionviaoxytocinreceptorexpression
AT tatekitsutsui molecularanalysisofparturitionviaoxytocinreceptorexpression
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