Gankyrin Drives Malignant Transformation of Gastric Cancer and Alleviates Oxidative Stress via mTORC1 Activation
Gastric cancer, as a malignant epithelial tumor, is a major health threat leading to poor overall survival and death. It is usually diagnosed at an advanced stage due to asymptomatic or only nonspecific early symptoms. The present study demonstrated that gankyrin contributes to the early malignant t...
Main Authors: | Bo Huang, Weiyang Cai, Qian Wang, Feng Liu, Ming Xu, Yanjie Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2018-01-01
|
Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2018/9480316 |
Similar Items
-
Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
by: Haiyang Tang, PhD, et al.
Published: (2018-12-01) -
mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
by: Xiaolei Ding, et al.
Published: (2016-10-01) -
mTORC1 and mTORC2 differentially promote natural killer cell development
by: Chao Yang, et al.
Published: (2018-05-01) -
mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
by: Jin Young Yang, et al.
Published: (2019-06-01) -
LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
by: Marcelle C. Ribeiro, et al.
Published: (2018-07-01)