Cellular Signaling Networks Function as Generalized Wiener-Kolmogorov Filters to Suppress Noise

Cellular signaling involves the transmission of environmental information through cascades of stochastic biochemical reactions, inevitably introducing noise that compromises signal fidelity. Each stage of the cascade often takes the form of a kinase-phosphatase push-pull network, a basic unit of sig...

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Bibliographic Details
Main Authors: Michael Hinczewski, D. Thirumalai
Format: Article
Language:English
Published: American Physical Society 2014-10-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.4.041017