Column-Free Purification Methods for Recombinant Proteins Using Self-Cleaving Aggregating Tags

Conventional column chromatography processes to purify recombinant proteins are associated with high production costs and slow volumetric throughput at both laboratory and large scale. Non-chromatographic purifications based on selective aggregating tags have the potential to reduce costs with accep...

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Bibliographic Details
Main Authors: Yamin Fan, Jackelyn M. Miozzi, Samuel D. Stimple, Tzu-Chiang Han, David W. Wood
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Polymers
Subjects:
Online Access:http://www.mdpi.com/2073-4360/10/5/468