Type I versus type II cytokine levels as a function of SOD1 G93A mouse amyotrophic lateral sclerosis disease progression

Type I versus type II cytokine levels as a function of SOD1 G93A mouse amyotrophic lateral sclerosis disease progression

Amyotrophic Lateral Sclerosis (ALS) is a fatal motoneuron disease that is characterized by the degradation of neurons throughout the central nervous system. Inflammation have been cited a key contributor to ALS neurodegeneration, but the timeline of cytokine upregulation remains unresolved. The goal...

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Bibliographic Details
Main Authors: Amilia eJeyachandran, Benjamin eMertens, Eric A McKissick, Cassie S Mitchell
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Amyotrophic Lateral Sclerosis
Homeostasis
Inflammation
glia
astrocyte
cytokine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00462/full

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