Interactions between Calcium and Alpha-Synuclein in Neurodegeneration

In Parkinson’s disease and some atypical Parkinson’s syndromes, aggregation of the α-synuclein protein (α-syn) has been linked to neurodegeneration. Many triggers for pathological α-syn aggregation have been identified, including port-translational modifications, oxidative stress and raised metal i...

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Bibliographic Details
Main Authors: Alex Rcom-H'cheo-Gauthier, Jacob Goodwin, Dean L. Pountney
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/4/3/795