Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion
Chromosomal NUP98-PHF23 translocation is associated with an aggressive form of AML. Here, the authors report the molecular mechanisms by which NUP98-PHF23 recognizes the histone mark H3K4me3 and provide evidence of a direct link between the association of NUP98-PHD finger chimeras with H3K4me3-rich...
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Bibliographic Details
| Main Authors: |
Yi Zhang,
Yiran Guo,
Sheryl M. Gough,
Jinyong Zhang,
Kendra R. Vann,
Kuai Li,
Ling Cai,
Xiaobing Shi,
Peter D. Aplan,
Gang Greg Wang,
Tatiana G. Kutateladze |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-17098-4
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