Diphenyleneiodonium inhibits NF-κB activation and iNOS expression induced by IL-1β: involvement of reactive oxygen species

Diphenyleneiodonium inhibits NF-κB activation and iNOS expression induced by IL-1β: involvement of reactive oxygen species

Aims: In this work, we studied the mechanisms by which diphenyleneiodonium chloride (DPI) inhibits nitric oxide (NO) synthesis induced by the pro-inflammatory cytokine interleukin-1β (IL-1) in bovine articular chondrocytes. To achieve this, we evaluated the ability of DPI to inhibit the expression a...

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Bibliographic Details
Main Authors:	A. Ferreira Mendes, A. Pato Carvalho, M. Margarida Caramona, M. Celeste Lopes
Format:	Article
Language:	English
Published:	Hindawi Limited 2001-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1080/09629350120080401

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