TRAIL promotes hepatocellular carcinoma apoptosis and inhibits proliferation and migration via interacting with IER3

TRAIL promotes hepatocellular carcinoma apoptosis and inhibits proliferation and migration via interacting with IER3

Abstract Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce substantial cytotoxicity in tumor cells but rarely exert cytotoxic activity on non-transformed cells. In the present study, we therefore evaluated interactions between TRAIL and IER3 via co-immunoprecipitation and im...

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Bibliographic Details
Main Authors: Shihai Liu, Jing Qiu, Guifang He, Weitai He, Changchang Liu, Duo Cai, Huazheng Pan
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cancer Cell International
Subjects:
Tumor necrosis factor-related apoptosis-inducing ligand
Wnt pathway
Hepatocellular carcinoma
Online Access:https://doi.org/10.1186/s12935-020-01724-8

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