The fission yeast stress-responsive MAPK pathway promotes meiosis via the phosphorylation of Pol II CTD in response to environmental and feedback cues.

The RRM-type RNA-binding protein Mei2 is a master regulator of meiosis in fission yeast, in which it stabilizes meiosis-specific mRNAs by blocking their destruction. Artificial activation of Mei2 can provoke the entire meiotic process, and it is suspected that Mei2 may do more than the stabilization...

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Bibliographic Details
Main Authors: Yuko Sukegawa, Akira Yamashita, Masayuki Yamamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3228818?pdf=render