Determination of the physical state of a drug in amorphous solid dispersions using artificial neural networks and ATR-FTIR spectroscopy
The objective of the present study was to evaluate the use of artificial neural networks (ANNs) in the development of a new chemometric model that will be able to simultaneously distinguish and quantify the percentage of the crystalline and the neat amorphous drug located within the drug-rich amorph...
Main Authors: | Afroditi Kapourani, Vasiliki Valkanioti, Konstantinos N. Kontogiannopoulos, Panagiotis Barmpalexis |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | International Journal of Pharmaceutics: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156720300268 |
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