The Long-Term Evolutionary History of Gradual Reduction of CpG Dinucleotides in the SARS-CoV-2 Lineage

Recent studies suggested that the fraction of CG dinucleotides (CpG) is severely reduced in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CpG deficiency was predicted to be the adaptive response of the virus to evade degradation of the viral RNA by the antiviral zin...

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Bibliographic Details
Main Author: Sankar Subramanian
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/1/52