NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells

NKX2.5 is expressed in papillary thyroid carcinomas and regulates differentiation in thyroid cells

Abstract Background NKX2.5 is a transcription factor transiently expressed during thyroid organogenesis. Recently, several works have pointed out the oncogenic role of NKX2.5 in a variety of tumors. We therefore hypothesized that NKX2.5 could also play a role in thyroid cancer. Methods The validatio...

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Bibliographic Details
Main Authors: Ricardo Cortez Cardoso Penha, Luisa Aguirre Buexm, Fabiana Resende Rodrigues, Taciana Padilha de Castro, Maria Carolina S. Santos, Rodrigo Soares Fortunato, Denise P. Carvalho, Luciene C. Cardoso-Weide, Andrea C. F. Ferreira
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
NKX2.5
Thyroid cancer
Persistence/recurrence
Papillary thyroid carcinoma
Differentiation
Iodide uptake
Online Access:http://link.springer.com/article/10.1186/s12885-018-4399-1

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http://link.springer.com/article/10.1186/s12885-018-4399-1

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