DNA instability in replicating Huntington's disease lymphoblasts
<p>Abstract</p> <p>Background</p> <p>The expanded CAG repeat in the Huntington's disease (HD) gene may display tissue-specific variability (e.g. triplet mosaicism) in repeat length, the longest mutations involving mitotic (germ and glial cells) and postmitotic (neu...
Main Authors: | Frati Luigi, Ragona Giuseppe, Martino Tiziana, Maglione Vittorio, Cannella Milena, Li Guo-Min, Squitieri Ferdinando |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-02-01
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Series: | BMC Medical Genetics |
Online Access: | http://www.biomedcentral.com/1471-2350/10/11 |
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