Role of KCNQ potassium channels in stress-induced deficit of working memory

The prefrontal cortex (PFC) mediates higher cognition but is impaired by stress exposure when high levels of catecholamines activate calcium-cAMP-protein kinase A (PKA) signaling. The current study examined whether stress and increased cAMP-PKA signaling in rat medial PFC (mPFC) reduce pyramidal cel...

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Bibliographic Details
Main Authors: Amy F.T. Arnsten, Lu E. Jin, Nao J. Gamo, Brian Ramos, Constantinos D. Paspalas, Yury M. Morozov, Anna Kata, Nigel S. Bamford, Mark F. Yeckel, Leonard K. Kaczmarek, Lynda El-Hassar
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Neurobiology of Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289519300396