A Purified Serine Protease from Nereis virens and Its Impaction of Apoptosis on Human Lung Cancer Cells

A Purified Serine Protease from Nereis virens and Its Impaction of Apoptosis on Human Lung Cancer Cells

Nereis active protease (NAP) is a novel fibrinolytic active serine protease from the polychaete Nereis virens. In this study, NAP was purified from Nereis virens and the effects of NAP on human lung cancer cells were investigated. Our results indicated that NAP inhibited the proliferation and induce...

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Bibliographic Details
Main Authors: Yunping Tang, Fangmiao Yu, Guomei Zhang, Zuisu Yang, Fangfang Huang, Guofang Ding
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
Nereis virens
serine protease
lung cancer
apoptosis
mitochondrial dysfunction
Online Access:https://www.mdpi.com/1420-3049/22/7/1123

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