Metabolome Shift in Both Metastatic Breast Cancer Cells and Astrocytes Which May Contribute to the Tumor Microenvironment

Metabolome Shift in Both Metastatic Breast Cancer Cells and Astrocytes Which May Contribute to the Tumor Microenvironment

The role of astrocytes in the periphery of metastatic brain tumors is unclear. Since astrocytes regulate central nervous metabolism, we hypothesized that changes in astrocytes induced by contact with cancer cells would appear in the metabolome of both cells and contribute to malignant transformation...

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Bibliographic Details
Main Authors: Hiromi Sato, Ayaka Shimizu, Toya Okawa, Miaki Uzu, Momoko Goto, Akihiro Hisaka
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
metabolome shift
astrocyte
metastatic brain tumor
glutamate
Online Access:https://www.mdpi.com/1422-0067/22/14/7430

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