Combining protein and metabolic engineering strategies for biosynthesis of melatonin in Escherichia coli

Combining protein and metabolic engineering strategies for biosynthesis of melatonin in Escherichia coli

Abstract Background Melatonin has attracted substantial attention because of its excellent prospects for both medical applications and crop improvement. The microbial production of melatonin is a safer and more promising alternative to chemical synthesis approaches. Researchers have failed to produc...

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Bibliographic Details
Main Authors: Yanfeng Zhang, Yongzhi He, Nan Zhang, JiaJia Gan, Shan Zhang, Zhiyang Dong
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Microbial Cell Factories
Subjects:
Melatonin
N-acetylserotonin
Metabolic engineering
Streptomyces albulus
S-adenosylmethionine
Online Access:https://doi.org/10.1186/s12934-021-01662-8

Internet

https://doi.org/10.1186/s12934-021-01662-8

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