DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

5-hydroxymethylation of cysteine (5-hmC) plays a role in epigenetic regulation. Here the authors analyse the hydroxymethylome in embryonic, neonatal, adult and hypertrophic mouse cardiomyocytes and show that the dynamic modulation of hydroxymethylated DNA is important for cardiomyocyte gene expressi...

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Bibliographic Details
Main Authors: Carolina M. Greco, Paolo Kunderfranco, Marcello Rubino, Veronica Larcher, Pierluigi Carullo, Achille Anselmo, Kerstin Kurz, Thomas Carell, Andrea Angius, Michael V. G. Latronico, Roberto Papait, Gianluigi Condorelli
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12418

Internet

https://doi.org/10.1038/ncomms12418

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