Electrofusion Stimulation Is an Independent Factor of Chromosome Abnormality in Mice Oocytes Reconstructed via Spindle Transfer

Electrofusion Stimulation Is an Independent Factor of Chromosome Abnormality in Mice Oocytes Reconstructed via Spindle Transfer

Oocytes reconstructed by spindle transfer (ST) are prone to chromosome abnormality, which is speculated to be caused by mechanical interference or premature activation, the mechanism is controversial. In this study, C57BL/6N oocytes were used as the model, and electrofusion ST was performed under no...

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Bibliographic Details
Main Authors: Wei Wang, Suxia Shao, Wei Chen, Weizhou Wang, Yunhai Chuai, Yunfei Li, Yiming Guo, Shujie Han, Mingming Shu, Qihang Wang, Lei Zhang, Wei Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Endocrinology
Subjects:
spindle transfer
electrofusion
electrofusion stimulation
premature activation
chromosome abnormality
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.705837/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.705837/full

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