The Evolving Concept of the Blood Brain Barrier (BBB): From a Single Static Barrier to a Heterogeneous and Dynamic Relay Center

The Evolving Concept of the Blood Brain Barrier (BBB): From a Single Static Barrier to a Heterogeneous and Dynamic Relay Center

The blood–brain barrier (BBB) helps maintain a tightly regulated microenvironment for optimal central nervous system (CNS) homeostasis and facilitates communications with the peripheral circulation. The brain endothelial cells, lining the brain’s vasculature, maintain close interactions with surroun...

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Bibliographic Details
Main Authors: Andres Villabona-Rueda, Clara Erice, Carlos A. Pardo, Monique F. Stins
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
cerebral endothelial cells
blood–brain barrier
neurovascular unit
brain cellular heterogeneity
vascular heterogeneity
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00405/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00405/full

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