Effects of AgRP inhibition on energy balance and metabolism in rodent models.

Activation of brain melanocortin-4 receptors (MC4-R) by α-melanocyte-stimulating hormone (MSH) or inhibition by agouti-related protein (AgRP) regulates food intake and energy expenditure and can modulate neuroendocrine responses to changes in energy balance. To examine the effects of AgRP inhibition...

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Bibliographic Details
Main Authors: Roxanne Dutia, Andrea J Kim, Matthew Modes, Robert Rothlein, Jane M Shen, Ye Edward Tian, Jumana Ihbais, Sam F Victory, Carmen Valcarce, Sharon L Wardlaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3675096?pdf=render