Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells

Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells

<p>Abstract</p> <p>Heparanase is an endoglycosidase that degrades heparan sulfate, the main polysaccharide constituent of the extracellular matrix (ECM) and basement membrane. Expression of the heparanase gene is associated with the invasion and metastatic potential of a variety of...

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Bibliographic Details
Main Authors: Zheng Xuguang, Zhang Xuepeng, Zhang Zheng, Kalkanis Steven N, Jiang Feng, Hong Xin, Jiang Hao, Mikkelsen Tom, Chopp Michael
Format: Article
Language:English
Published: BMC 2008-07-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/23

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