FT- SERS Study of Adriamycin - DNA Intraction

FT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin  with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 s...

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Main Author: Amanollah Aminzadeh
Format: Article
Language:English
Published: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 2003-04-01
Series:Iranian Journal of Chemistry & Chemical Engineering
Subjects:
dna
Online Access:http://www.ijcce.ac.ir/article_8182_d9a65a0c544c252a25fe2d8816c121e1.pdf
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spelling doaj-e4472ad32c7a4b72bb8e8d9bd51c00e82020-11-25T03:41:59ZengIranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECRIranian Journal of Chemistry & Chemical Engineering 1021-99861021-99862003-04-012219118182FT- SERS Study of Adriamycin - DNA IntractionAmanollah Aminzadeh0College of Chemistry, Isfahan University of echnology, Isfahan 84154, I. R. IranFT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin  with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 suggests that ring D of adriamycin is not involved in the intercalation process.http://www.ijcce.ac.ir/article_8182_d9a65a0c544c252a25fe2d8816c121e1.pdfft-sersadriamycindnamedical researchantitumor activity
collection DOAJ
language English
format Article
sources DOAJ
author Amanollah Aminzadeh
spellingShingle Amanollah Aminzadeh
FT- SERS Study of Adriamycin - DNA Intraction
Iranian Journal of Chemistry & Chemical Engineering
ft-sers
adriamycin
dna
medical research
antitumor activity
author_facet Amanollah Aminzadeh
author_sort Amanollah Aminzadeh
title FT- SERS Study of Adriamycin - DNA Intraction
title_short FT- SERS Study of Adriamycin - DNA Intraction
title_full FT- SERS Study of Adriamycin - DNA Intraction
title_fullStr FT- SERS Study of Adriamycin - DNA Intraction
title_full_unstemmed FT- SERS Study of Adriamycin - DNA Intraction
title_sort ft- sers study of adriamycin - dna intraction
publisher Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR
series Iranian Journal of Chemistry & Chemical Engineering
issn 1021-9986
1021-9986
publishDate 2003-04-01
description FT-SERS (Fourier Transform Surface Enhanced Raman Scattering) of adriamycin and its complex with DNA is reported. It is shown that in agreement with previous Raman studies the interaction of adriamycin  with DNA takes place through an intercalation mechanism. The presence of a new band at 731 cm-1 suggests that ring D of adriamycin is not involved in the intercalation process.
topic ft-sers
adriamycin
dna
medical research
antitumor activity
url http://www.ijcce.ac.ir/article_8182_d9a65a0c544c252a25fe2d8816c121e1.pdf
work_keys_str_mv AT amanollahaminzadeh ftsersstudyofadriamycindnaintraction
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