Genetic polymorphisms and cerebrovascular disease in children with sickle cell anemia from Rio de Janeiro, Brazil

Genetic polymorphisms and cerebrovascular disease in children with sickle cell anemia from Rio de Janeiro, Brazil

The aim of the present work was to examine possible genetic risk factors related to the occurrence of cerebrovascular disease (CVD) in Brazilian population, the frequency of βS-globin gene haplotypes and co-inheritance with α-thalassemia (-α3.7kb) and single nucleotide polymorphism of methylenetetra...

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Main Authors: Isaac Lima da Silva Filho, Ana Claudia Celestino Bezerra Leite, Patrícia Gomes Moura, Georgina Severo Ribeiro, Andréa Cony Cavalcante, Flávia Carolina Marques de Azevedo, Maria José de Andrada-Serpa
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2011-06-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
anemia falciforme
acidente vascular cerebral
talassemia alfa
globinas beta
polimorfismo genético
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000400004&lng=en&tlng=en

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