Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules

Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules

<p>Abstract</p> <p>Background</p> <p>Myotonic dystrophy type 1 (DM1) is the most common muscle dystrophy in adults. The disease is caused by a triplet expansion in the 3'end of the myotonic dystrophy protein kinase (<it>DMPK) </it>gene. In order to deve...

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Bibliographic Details
Main Authors: Larsen Jan, Pettersson Olof J, Jakobsen Maria, Thomsen Rune, Pedersen Christina B, Hertz Jens M, Gregersen Niels, Corydon Thomas J, Jensen Thomas G
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/4/490

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