miR526b and miR655 Induce Oxidative Stress in Breast Cancer

miR526b and miR655 Induce Oxidative Stress in Breast Cancer

In eukaryotes, overproduction of reactive oxygen species (ROS) causes oxidative stress, which contributes to chronic inflammation and cancer. MicroRNAs (miRNAs) are small, endogenously produced RNAs that play a major role in cancer progression. We established that overexpression of miR526b/miR655 pr...

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Bibliographic Details
Main Authors: Bonita Shin, Riley Feser, Braydon Nault, Stephanie Hunter, Sujit Maiti, Kingsley Chukwunonso Ugwuagbo, Mousumi Majumder
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
MicroRNA (miRNA)
miR526b
miR655
oxidative stress
reactive oxygen species (ROS)
superoxide (SO)
Thioredoxin Reductase 1 (TXNRD1)
breast cancer
Online Access:https://www.mdpi.com/1422-0067/20/16/4039

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