Development and Clinical Application of a Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for SARS-CoV-2 Infection

Development and Clinical Application of a Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for SARS-CoV-2 Infection

We developed a visual and rapid reverse transcription–loop-mediated isothermal amplification (RT-LAMP) assay targeting the S gene for SARS-CoV-2 infection. The strength of our study was that we validated the RT-LAMP assay using 481 clinical respiratory samples from two prospective cohorts of suspect...

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Bibliographic Details
Main Authors: Xuejiao Hu, Qianyun Deng, Junmin Li, Jierong Chen, Zixia Wang, Xiqin Zhang, Zhixin Fang, Haijian Li, Yunhu Zhao, Pan Yu, Wenmin Li, Xiaoming Wang, Shan Li, Lei Zhang, Tieying Hou
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSphere
Subjects:
rt-lamp
sars-cov-2
covid-19
asymptomatic carriers
clinical diagnosis
Online Access:https://doi.org/10.1128/mSphere.00808-20

Internet

https://doi.org/10.1128/mSphere.00808-20

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