Permeability of the windows of the brain: feasibility of dynamic contrast-enhanced MRI of the circumventricular organs

Permeability of the windows of the brain: feasibility of dynamic contrast-enhanced MRI of the circumventricular organs

Abstract Background Circumventricular organs (CVOs) are small structures without a blood–brain barrier surrounding the brain ventricles that serve homeostasic functions and facilitate communication between the blood, cerebrospinal fluid and brain. Secretory CVOs release peptides and sensory CVOs reg...

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Bibliographic Details
Main Authors: Inge C. M. Verheggen, Joost J. A. de Jong, Martin P. J. van Boxtel, Alida A. Postma, Frans R. J. Verhey, Jacobus F. A. Jansen, Walter H. Backes
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Fluids and Barriers of the CNS
Subjects:
Circumventricular organs
Dynamic contrast-enhanced magnetic resonance imaging
Permeability
Pharmacokinetic modeling
Online Access:http://link.springer.com/article/10.1186/s12987-020-00228-x

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