Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.

Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.

Age-related changes in hepatic triglyceride formation have been described in developing rats. Triglyceride formation was measured in vitro in the presence of [14C]glycerol-3-phosphate, palmitate, ATP, CoA, and Mg2+ by using liver homogenates and microsomal fractions derived from various age groups o...

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Bibliographic Details
Main Authors: S C Jamdar, M Moon, S Bow, H J Fallon
Format: Article
Language:English
Published: Elsevier 1978-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520412787
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spelling doaj-e41f8755eb7f4193a7f0e40011f6b4832021-04-24T05:53:25ZengElsevierJournal of Lipid Research0022-22751978-08-01196763770Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.S C JamdarM MoonS BowH J FallonAge-related changes in hepatic triglyceride formation have been described in developing rats. Triglyceride formation was measured in vitro in the presence of [14C]glycerol-3-phosphate, palmitate, ATP, CoA, and Mg2+ by using liver homogenates and microsomal fractions derived from various age groups of animals. Triglyceride formation was most active in one-day-old rats and then decrease with age. The increase in triglyceride formation following birth was prevented by the administration of puromycin or by denying suckling. In addition, changes in plasma and hepatic triglyceride concentrations, were also determined as functions of age. These studies suggest that the age of the animal significantly influences triglyceride metabolism.http://www.sciencedirect.com/science/article/pii/S0022227520412787
collection DOAJ
language English
format Article
sources DOAJ
author S C Jamdar
M Moon
S Bow
H J Fallon
spellingShingle S C Jamdar
M Moon
S Bow
H J Fallon
Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.
Journal of Lipid Research
author_facet S C Jamdar
M Moon
S Bow
H J Fallon
author_sort S C Jamdar
title Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.
title_short Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.
title_full Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.
title_fullStr Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.
title_full_unstemmed Hepatic lipid metabolism. Age-related changes in triglyceride metabolism.
title_sort hepatic lipid metabolism. age-related changes in triglyceride metabolism.
publisher Elsevier
series Journal of Lipid Research
issn 0022-2275
publishDate 1978-08-01
description Age-related changes in hepatic triglyceride formation have been described in developing rats. Triglyceride formation was measured in vitro in the presence of [14C]glycerol-3-phosphate, palmitate, ATP, CoA, and Mg2+ by using liver homogenates and microsomal fractions derived from various age groups of animals. Triglyceride formation was most active in one-day-old rats and then decrease with age. The increase in triglyceride formation following birth was prevented by the administration of puromycin or by denying suckling. In addition, changes in plasma and hepatic triglyceride concentrations, were also determined as functions of age. These studies suggest that the age of the animal significantly influences triglyceride metabolism.
url http://www.sciencedirect.com/science/article/pii/S0022227520412787
work_keys_str_mv AT scjamdar hepaticlipidmetabolismagerelatedchangesintriglyceridemetabolism
AT mmoon hepaticlipidmetabolismagerelatedchangesintriglyceridemetabolism
AT sbow hepaticlipidmetabolismagerelatedchangesintriglyceridemetabolism
AT hjfallon hepaticlipidmetabolismagerelatedchangesintriglyceridemetabolism
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