Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

Abstract Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy because of their high immunomodulation ability, tropism towards inflamed and injured tissues, and their easy access and isolation. Currently, there are more than 1200 registered MSC clinical trials globall...

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Bibliographic Details
Main Authors: Wei-Zhan Zhuang, Yi-Heng Lin, Long-Jyun Su, Meng-Shiue Wu, Han-Yin Jeng, Huan-Cheng Chang, Yen-Hua Huang, Thai-Yen Ling
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Biomedical Science
Subjects:
Mesenchymal stem/stromal cell
Cell therapy
Systemic safety
biodistribution
Single cell imaging
Online Access:https://doi.org/10.1186/s12929-021-00725-7

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