Connective Tissue Growth Factor in Normal and Pathological Processes

Modern concepts about the role of connective tissue growth factor in various physiological and pathological processes are described in the review. Connective tissue growth factor regulates a variety of cellular functions, including proliferation, migration, adhesion, differentiation and synthesis of...

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Main Author:	S. V. Topolyanskaya
Format:	Article
Language:	Russian
Published:	SINAPS LLC 2020-07-01
Series:	Arhivʺ Vnutrennej Mediciny
Subjects:	connective tissue growth factor fibrosis nephrosclerosis chondrogenesis osteogenesis aging
Online Access:	https://www.medarhive.ru/jour/article/view/1070

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spelling	doaj-e417eab649d241bd9afca30ce29df4d72021-07-29T08:11:37ZrusSINAPS LLCArhivʺ Vnutrennej Mediciny2226-67042411-65642020-07-0110425426110.20514/2226-6704-2020-10-4-254-261798Connective Tissue Growth Factor in Normal and Pathological ProcessesS. V. Topolyanskaya0I.M. Sechenov First Moscow State Medical University (Sechenov University), RF Health Ministry, Hospital Therapy Department № 2Modern concepts about the role of connective tissue growth factor in various physiological and pathological processes are described in the review. Connective tissue growth factor regulates a variety of cellular functions, including proliferation, migration, adhesion, differentiation and synthesis of extracellular matrix proteins in cells of different types. This factor is also involved in more complex biological processes of angiogenesis, chondrogenesis, wound healing, fibrosis and oncogenesis. Increased expression of connective tissue growth factor is observed in different cardiovascular and oncological diseases. Potential role of this growth factor in regulation of cellular senescence and aging processes is also discussed.https://www.medarhive.ru/jour/article/view/1070connective tissue growth factorfibrosisnephrosclerosischondrogenesisosteogenesisaging
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	S. V. Topolyanskaya
spellingShingle	S. V. Topolyanskaya Connective Tissue Growth Factor in Normal and Pathological Processes Arhivʺ Vnutrennej Mediciny connective tissue growth factor fibrosis nephrosclerosis chondrogenesis osteogenesis aging
author_facet	S. V. Topolyanskaya
author_sort	S. V. Topolyanskaya
title	Connective Tissue Growth Factor in Normal and Pathological Processes
title_short	Connective Tissue Growth Factor in Normal and Pathological Processes
title_full	Connective Tissue Growth Factor in Normal and Pathological Processes
title_fullStr	Connective Tissue Growth Factor in Normal and Pathological Processes
title_full_unstemmed	Connective Tissue Growth Factor in Normal and Pathological Processes
title_sort	connective tissue growth factor in normal and pathological processes
publisher	SINAPS LLC
series	Arhivʺ Vnutrennej Mediciny
issn	2226-6704 2411-6564
publishDate	2020-07-01
description	Modern concepts about the role of connective tissue growth factor in various physiological and pathological processes are described in the review. Connective tissue growth factor regulates a variety of cellular functions, including proliferation, migration, adhesion, differentiation and synthesis of extracellular matrix proteins in cells of different types. This factor is also involved in more complex biological processes of angiogenesis, chondrogenesis, wound healing, fibrosis and oncogenesis. Increased expression of connective tissue growth factor is observed in different cardiovascular and oncological diseases. Potential role of this growth factor in regulation of cellular senescence and aging processes is also discussed.
topic	connective tissue growth factor fibrosis nephrosclerosis chondrogenesis osteogenesis aging
url	https://www.medarhive.ru/jour/article/view/1070
work_keys_str_mv	AT svtopolyanskaya connectivetissuegrowthfactorinnormalandpathologicalprocesses
_version_	1721257182265081856

Connective Tissue Growth Factor in Normal and Pathological Processes

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