Polymorphisms of GLP-1 Receptor Gene and Response to GLP-1 Analogue in Patients with Poorly Controlled Type 2 Diabetes

Polymorphisms of GLP-1 Receptor Gene and Response to GLP-1 Analogue in Patients with Poorly Controlled Type 2 Diabetes

Aim. The relationship between genetic polymorphisms of the glucagon-like peptide-1 (GLP-1) receptor (GLP1R) gene and unresponsiveness to GLP-1 analogue treatment in patients with poorly controlled type 2 diabetes mellitus (DM) is unclear. Methods. Thirty-six patients with poorly controlled type 2 DM...

Full description

Bibliographic Details
Main Authors:	Chia-Hung Lin, Yun-Shien Lee, Yu-Yao Huang, Sheng-Hwu Hsieh, Zih-Syuan Chen, Chi-Neu Tsai
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2015/176949

Similar Items

Synthesis and Evaluation of Optical and PET GLP-1 Peptide Analogues for GLP-1R Imaging
by: Babak Behnam Azad, et al.
Published: (2015-01-01)

Purslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes
by: Sara Heidarzadeh, et al.
Published: (2013-01-01)

Purslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes
by: Roja Daliri, et al.
Published: (2013-01-01)

Allosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptor.
by: Naichang Li, et al.
Published: (2012-01-01)

Novel GLP-1 fusion chimera as potent long acting GLP-1 receptor agonist.
by: Qinghua Wang, et al.
Published: (2010-09-01)

Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD
by: Marta Seghieri, et al.
Published: (2018-11-01)

Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice
by: Mette Simone Aae Madsen, et al.
Published: (2019-10-01)

GLP-1/GLP-1R Signaling in Regulation of Adipocyte Differentiation and Lipogenesis
by: Jicui Chen, et al.
Published: (2017-06-01)

GLP-1 Receptor Agonists and Kidney Protection
by: Eulalia Valentina Greco, et al.
Published: (2019-05-01)

Peptide-oligourea hybrids analogue of GLP-1 with improved action in vivo
by: Juliette Fremaux, et al.
Published: (2019-02-01)

Effect of GLP-1/GLP-1R on the Polarization of Macrophages in the Occurrence and Development of Atherosclerosis
by: Li Yang, et al.
Published: (2021-01-01)

Protective Effects of GLP-1 Analogue (Liraglutide) Against Amyloid β-induced Neurotoxicity
by: Shan-KO Tsai, et al.
Published: (2016)

Role and development of GLP-1 receptor agonists in the management of diabetes
by: Chee&nbsp;W Chia, et al.
Published: (2009-05-01)

Preparation of the recombinant GLP-1
by: WU YAN RU, et al.
Published: (2017)

Glucolipotoxicity and GLP-1 secretion
by: Jung-Hee Hong, et al.
Published: (2021-08-01)

Glucagon, GLP-1 and Thermogenesis
by: Ismael González-García, et al.
Published: (2019-07-01)

GLP-1 and Intestinal Diseases
by: Jenna Elizabeth Hunt, et al.
Published: (2021-04-01)

GLP-1 Receptor: A New Target for Sepsis
by: Fuxun Yang, et al.
Published: (2021-07-01)

Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor
by: Ghina Shaaban, et al.
Published: (2016-12-01)

GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects
by: Xin Zhao, et al.
Published: (2021-08-01)

Swedish diabetes patients’ experiences of using GLP-1 receptor agonists (GLP-1 RAs) : A qualitative interview study.
by: Ekenberg, Marie
Published: (2021)

GLP-1 REGULATES PROLIFERATION OF GLP-1 SECRETING CELLS THROUGH A FEEDBACK MECHANISM
by: Abdullahi Mohamed, Mohamed
Published: (2010)

Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men.
by: Niina Matikainen, et al.
Published: (2016-01-01)

A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor
by: Noura Al-Zamel, et al.
Published: (2019-07-01)

Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc.
by: Yi Yang, et al.
Published: (2016-01-01)

Increasing GLP-1 Circulating Levels by Bariatric Surgery or by GLP-1 Receptor Agonists Therapy: Why Are the Clinical Consequences so Different?
by: Chloé Amouyal, et al.
Published: (2016-01-01)

Can glucagon-like peptide-1 (GLP-1) analogues make neuroprotection a reality?
by: Maryna V Basalay, et al.
Published: (2020-01-01)

Mutagenesis facilitated crystallization of GLP-1R
by: Yueming Xu, et al.
Published: (2019-11-01)

Targeting GLP-1 receptor trafficking to improve agonist efficacy
by: Ben Jones, et al.
Published: (2018-04-01)

GLP-1 receptor agonists and cardiovascular outcome trials: An update
by: Eirini Andrikou, et al.
Published: (2019-11-01)

Induction of Energy Expenditure by Sitagliptin Is Dependent on GLP-1 Receptor.
by: Felicia Goldsmith, et al.
Published: (2015-01-01)

Emerging role of GLP-1 receptor agonists in the treatment of obesity
by: Neff LM
Published: (2010-07-01)

Emerging role of GLP-1 receptor agonists in the treatment of obesity
by: Lisa M Neff, et al.
Published: (2010-07-01)

Simultaneous analyses of carbohydrate-mediated serum GLP-1 and GLP-2 and duodenal receptor expression in children with and without celiac disease
by: Marianna Rachmiel, et al.
Published: (2019-04-01)

The role and therapeutic potential of GLP-1 analogues as a treatment for type 2 diabetes
by: Lavery, Kerry Susan
Published: (2006)

Serum levels of glucagon-like peptide (GLP)-1 and GLP-2 in patients with Hashimoto′s thyroiditis
by: Yue Jin, et al.
Published: (2015-01-01)

Lateral Septal GLP-1 Pathways

Cardioprotective effects of GLP‐1(28‐36a): A degraded metabolite or GLP‐1’s better half?
by: Yangyang Liu, et al.
Published: (2020-11-01)

Glucagon-like peptide 1 (GLP-1)
by: T.D. Müller, et al.
Published: (2019-12-01)

Glucagon receptor antagonist upregulates circulating GLP-1 level by promoting intestinal L-cell proliferation and GLP-1 production in type 2 diabetes
by: Shan Lang, et al.
Published: (2020-04-01)