6-Amino-1-benzyl-4-(4-chlorophenyl)-3-(4-pyridyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

6-Amino-1-benzyl-4-(4-chlorophenyl)-3-(4-pyridyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

The crystal structure of the title compound, C25H18ClN5O, was determined in the course of our studies on the synthesis of 1,4-dihydropyrano[2,3-c]pyrazole as an inhibitor of the p38 mitogen-activated protein kinase (MAPK). The compound was prepared via a base-catalysed synthesis from 1-benzyl-3-(4-p...

Full description

Bibliographic Details
Main Authors:	Stefan Laufer, Dieter Schollmeyer, Frank Lehmann
Format:	Article
Language:	English
Published:	International Union of Crystallography 2008-04-01
Series:	Acta Crystallographica Section E
Online Access:	http://scripts.iucr.org/cgi-bin/paper?S160053680800487X

Similar Items

6-Amino-3-methyl-4-(3,4,5-trimethoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
by: Naresh Sharma, et al.
Published: (2014-08-01)

3-(4-Fluorophenyl)-2-(4-pyridyl)pyrido[2,3-b]pyrazine
by: Pierre Koch, et al.
Published: (2009-10-01)

2-(4-Fluorophenyl)-3-(4-pyridyl)pyrido[2,3-b]pyrazine
by: Pierre Koch, et al.
Published: (2009-10-01)

5-(4-Fluorophenyl)-4-(4-pyridyl)-1,3-oxazol-2-amine
by: Pierre Koch, et al.
Published: (2010-04-01)

N-[(3RS,4SR)-1-Benzyl-4-methylpiperidin-3-yl]-1-(4-methylphenylsulfonyl)-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-amine
by: Ellen Pfaffenrot, et al.
Published: (2012-10-01)

1-[(3RS,4RS)-1-Benzyl-4-methylpiperidin-3-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine hemihydrate
by: Ellen Pfaffenrot, et al.
Published: (2012-10-01)

tert-Butyl N-benzyl-N-[4-(4-fluorobenzoylmethyl)-2-pyridyl]carbamate
by: Pierre Koch, et al.
Published: (2008-11-01)

N-[(3RS,4RS)-1-Benzyl-4-methylpiperidin-3-yl]-5-nitro-1-phenylsulfonyl-1H-pyrrolo[2,3-b]pyridine-4-amine
by: Ellen Pfaffenrot, et al.
Published: (2012-10-01)

Crystal structure of 6-amino-4-(3-bromo-4-methoxyphenyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile dimethyl sulfoxide monosolvate
by: Sammer Yousuf, et al.
Published: (2015-07-01)

N-{4-[3-(4-Fluorophenyl)pyrido[2,3-b]pyrazin-2-yl]-2-pyridyl}isopropylamine
by: Pierre Koch, et al.
Published: (2009-10-01)

A Practical Catalyst-Free Synthesis of 6-Amino-4 Alkyl/Aryl-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-carbonitrile in Aqueous Medium
by: Manisha Bihani, et al.
Published: (2013-01-01)

tert-Butyl N-benzyl-N-(4-methyl-2-pyridyl)carbamate
by: Pierre Koch, et al.
Published: (2008-11-01)

4-(4-Fluorophenyl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one
by: Stefan Laufer, et al.
Published: (2008-02-01)

4-(4-Fluorophenyl)-1-(4-nitrophenyl)-3-(pyridin-4-yl)-1H-pyrazol-5-amine
by: Stefan Laufer, et al.
Published: (2012-03-01)

4-(4-Fluorophenyl)-1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-5-amine
by: Stefan Laufer, et al.
Published: (2012-03-01)

4-[5-Amino-4-(4-fluorophenyl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl]benzonitrile
by: Bassam Abu Thaher, et al.
Published: (2012-04-01)

3-(4-Bromophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
by: Mahmoud Elkady, et al.
Published: (2012-12-01)

4-(4-Fluorophenyl)-3-(pyridin-4-yl)-1-(2,4,6-trichlorophenyl)-1H-pyrazol-5-amine
by: Bassam Abu Thaher, et al.
Published: (2012-09-01)

3-(4-Fluorophenyl)-6-methoxy-2-(4-pyridyl)quinoxaline
by: Hartmut Jahns, et al.
Published: (2009-07-01)

6-(4-Chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-carbaldehyde
by: Peter R. W. E. F. Keck, et al.
Published: (2011-09-01)

10-Methyl-2-oxo-4-phenyl-2,11-dihydropyrano[2,3-a]carbazole-3-carbonitrile
by: A. Thiruvalluvar, et al.
Published: (2013-06-01)

[3-(4-Chlorophenyl)-5-hydroxy-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl](3-pyridyl)methanone
by: B. Kalluraya, et al.
Published: (2008-12-01)

N-{4-[4-(4-Fluorophenyl)-1-(2-methoxyethyl)-2-methylsulfanyl-1H-imidazol-5-yl]-2-pyridyl}-2-methyl-3-phenylpropionamide
by: Stefan Laufer, et al.
Published: (2009-12-01)

3-(4-Chlorophenyl)-1-[(E)-1-(4-chlorophenyl)-2-(4-methylphenylsulfanyl)ethenyl]-4-(4-methylphenylsulfanyl)-1H-pyrazole
by: P. Ramesh, et al.
Published: (2009-11-01)

3-(4-Chlorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
by: Hoong-Kun Fun, et al.
Published: (2011-07-01)

3-Oxo-5-(piperidin-1-yl)-2,3-dihydro-1H-pyrazole-4-carbonitrile
by: Wedad M. Al-Adiwish, et al.
Published: (2011-12-01)

Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines
by: E. Angeles, et al.
Published: (2001-07-01)

(2-Chlorophenyl)-3-methylchromeno[2,3-c]pyrazol-4(1H)-one
by: Wolfgang Holzer, et al.
Published: (2010-03-01)

4-Chloro-1-(4-methylphenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
by: Stefan Laufer, et al.
Published: (2009-12-01)

1-(4-Chlorophenyl)-1H-pyrazol-3-ol
by: Xiao-Yan Ren, et al.
Published: (2010-01-01)

1-[2-(Benzylamino)-4-pyridyl]-2-(4-fluorophenyl)ethane-1,2-dione
by: Hartmut Jahns, et al.
Published: (2009-06-01)

2-Amino-4-(4-chlorophenyl)-6-ferrocenylpyridine-3-carbonitrile
by: Shuiping Huang, et al.
Published: (2008-05-01)

Ethyl 2-benzyl-3-[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]-4,6-dioxo-5-phenyloctahydropyrrolo[3,4-c]pyrrole-1-carboxylate
by: P. Kamatchi, et al.
Published: (2012-02-01)

(E)-3-(4-Chlorophenyl)-3-[3-(4-chlorophenyl)-1H-pyrazol-1-yl]prop-2-enal
by: R. Manikannan, et al.
Published: (2010-10-01)

DABCO catalyzed rapid one-pot synthesis of 1,4-dihydropyrano [2,3-c] pyrazole derivatives in aqueous media
by: Amit S. Waghmare, et al.
Published: (2017-03-01)

3-(4-Chlorophenyl)-5-[4-(methylsulfanyl)phenyl]-1H-pyrazole
by: Ganesan Suresh, et al.
Published: (2016-04-01)

5-Amino-3-anilino-1H-pyrazole-4-carbonitrile
by: Shaaban K. Mohamed, et al.
Published: (2012-09-01)

2-(4-Chlorophenyl)-4-[1-(4-chlorophenyl)-3-methyl-1H-pyrazol-5-yl]-5-methyl-1H-pyrazol-3(2H)-one
by: Seik Weng Ng, et al.
Published: (2010-10-01)

5-Amino-1-(4-nitrophenyl)-1H-pyrazole-3-carbonitrile
by: Qiang-Hua Jiang, et al.
Published: (2012-01-01)

3-Acetyl-1,5-diphenyl-1H-pyrazole-4-carbonitrile
by: Hatem A. Abdel-Aziz, et al.
Published: (2012-04-01)

Cannot write session to /tmp/vufind_sessions/sess_b3520nk1k50gdvna7n7pdsn0l0