INFLUENCE OF PHARMACOLOGICAL CORRECTION ON THE QUALITY OF LIFE OF CHILDREN WITH FUNCTIONAL DYSPEPSIA

• Main Authors: Marina Mamenko, Hanna Drokh
• Format: Article
• Language: English
• Published: Scientific Route OÜ 2020-11-01
• Series: EUREKA: Health Sciences
• Subjects: functional gastrointestinal disorders; functional dyspepsia; quality of life; treatment.
• Online Access: http://journal.eu-jr.eu/health/article/view/1518

Objective: To study the influence of pharmacological psychocorrection with drugs derived from GABA on the quality of life of primary school-aged children with functional dyspepsia. Materials and methods. 80 children aged 6–12 years with FD have been examined. Children were divided into 4 groups: Group 1 – 20 patients who received γ-amino-β-phenylbutyric acid hydrochloride along with baseline therapy, Group 2 – 20 patients who received comprehensive treatment and calcium hopantenate, Group 3 – 20 children who received vitamin-mineral complex and protocol treatment, and Control Group – 20 children who received baseline treatment. Study Design: general clinical, instrumental, psychodiagnostic, statistical. Results. Using the PedsQL questionnaire, physical functioning disorders were found in children with FD – 97.5±1.2 % (78/80) of children, emotional functioning disorders – 91.3±1.6 % (73/80) of cases, functioning at school disorders – 88.8±2.7 % (71/80) of patients. During one-month case monitoring, children who took GABA drugs reported an improvement in the quality of life compared with baseline treatment and a group of children, who took a mineral-vitamin complex: physical functioning – (р1=0,016), (р2=0,03), emotional functioning – (р1˂0,001), (р2˂0,001), functioning in school – (р1=0,005), (р2=0,004). Conclusion. The use of γ-aminobutyric acid drugs is safe and effective and they significantly improve the quality of life of children with FD.