Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.

microRNAs (miRs) modulate the expression levels of mRNAs and proteins and can thus contribute to cancer initiation and progression. In addition to their intracelluar function, miRs are released from cells and shed into the circulation. We postulated that circulating miRs could provide insight into p...

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Bibliographic Details
Main Authors: Joseph J LaConti, Narayan Shivapurkar, Anju Preet, Anne Deslattes Mays, Ivana Peran, Sung Eun Kim, John L Marshall, Anna T Riegel, Anton Wellstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3124473?pdf=render