Resistin-Induced Endoplasmic Reticulum Stress Contributes to the Impairment of Insulin Signaling in Endothelium

Resistin-Induced Endoplasmic Reticulum Stress Contributes to the Impairment of Insulin Signaling in Endothelium

Background: Endoplasmic reticulum (ER) stress plays an important role in the pathogenesis of obesity, insulin resistance and cardiovascular diseases (CVDs). Impairment of insulin vascular action may represent a mechanism linking insulin resistance and CVDs. The present study tested the hypothesis th...

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Bibliographic Details
Main Authors: Jun Luo, Lei Huang, Aimei Wang, Yueyang Liu, Ruiping Cai, Weihong Li, Ming-Sheng Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
cardiovascular diseases
endothelial nitric oxide synthesis
endoplasmic reticulum stress
resistin
vascular insulin signaling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01226/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01226/full

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