Pathophysiological and Pharmacological Characteristics of <i>KCNJ5</i> 157-159delITE Somatic Mutation in Aldosterone-Producing Adenomas

Pathophysiological and Pharmacological Characteristics of <i>KCNJ5</i> 157-159delITE Somatic Mutation in Aldosterone-Producing Adenomas

Mutated channelopathy could play important roles in the pathogenesis of aldosterone-producing adenoma (APA). In this study, we identified a somatic mutation, <i>KCNJ5</i> 157-159delITE, and reported its immunohistological, pathophysiological and pharmacological characteristics. We conduc...

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Bibliographic Details
Main Authors: Kang-Yung Peng, Hung-Wei Liao, Jeff S. Chueh, Chien-Yuan Pan, Yen-Hung Lin, Yung-Ming Chen, Peng-Ying Chen, Chun-Lin Huang, Vin-Cent Wu
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
Aldosterone producing adenoma
<i>KCNJ5</i>
157-159delITE mutation
primary aldosteronism
Online Access:https://www.mdpi.com/2227-9059/9/8/1026

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