Roles of type VI collagen and decorin in human mesenchymal stem cell biophysics during chondrogenic differentiation

Roles of type VI collagen and decorin in human mesenchymal stem cell biophysics during chondrogenic differentiation

Human mesenchymal stem cells (hMSCs) induced towards chondrogenesis develop a pericellular matrix (PCM), rich in type VI collagen (ColVI) and proteoglycans such as decorin (DCN). Individual PCM protein functions still need to be elucidated to fully understand the mechanobiological role of this matri...

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Bibliographic Details
Main Authors: JD Twomey, PI Thakore, DA Hartman, EGH Myers, AH Hsieh
Format: Article
Language:English
Published: AO Research Institute Davos 2014-03-01
Series:European Cells & Materials
Subjects:
Pericellular matrix
human mesenchymal stem cell
type VI collagen
decorin
chondrogenesis
RNA interference
Online Access:http://www.ecmjournal.org/journal/papers/vol027/pdf/v027a17.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol027/pdf/v027a17.pdf

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