Transcriptomic analyses reveal the underlying pro-malignant functions of PTHR1 for osteosarcoma via activation of Wnt and angiogenesis pathways

Transcriptomic analyses reveal the underlying pro-malignant functions of PTHR1 for osteosarcoma via activation of Wnt and angiogenesis pathways

Abstract Background Increasing evidence has indicated parathyroid hormone type 1 receptor (PTHR1) plays important roles for the development and progression of osteosarcoma (OS). However, its function mechanisms remain unclear. The goal of this study was to further illuminate the roles of PTHR1 in OS...

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Bibliographic Details
Main Authors: Shenglong Li, Yujin Dong, Ke Wang, Zhe Wang, Xiaojing Zhang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteosarcoma
PTHR1
Wnt pathway
Angiogenesis
Inflammation
Online Access:http://link.springer.com/article/10.1186/s13018-017-0664-2

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